Dr Angus Prosser
Senior Research Fellow

Diagnosis and prognosis

Portrait image of Angus Prosser

Angus is a Senior Research Fellow within the Faculty of Medicine at the University of Southampton and Innovation Project Manager for the Southampton Emerging Therapies and Technologies (SETT) Centre.

Angus’s research interests include the optimisation of neuroimaging and other biomarkers to improve diagnosis and prognosis for those living with dementia or neurodegenerative disease, and the translation of novel technologies for patient benefit. His work with the SETT centre at University Hospital Southampton is focussed on pathway optimisation for development and testing of novel medical technologies and innovations….

Angus has considerable knowledge in translational study design and management and analysis of large datasets, and he is experienced in neuroimaging (structural and functional) analysis and processing.


Dr Angus Prosser
Health Sciences, Student Office, University of Southampton, Highfield, Southampton. SO17 1BJ

Room Number : SGH/CE114/MP807

recent publications:

Brain PET and SPECT imaging and quantification: a survey of the current status in the UK
Michopoulou SK, Dickson JC, Gardner GG, Gee TR, Fenwick AJ, Melhuish T, Monaghan CA, O'Brien N, Prosser AMJ, Scott CJ, Staff RT and Taylor J
With disease-modifying therapies in development for neurological disorders, quantitative brain imaging techniques become increasingly relevant for objective early diagnosis and assessment of response to treatment. The aim of this study was to evaluate the use of Brain SPECT and PET scans in the UK and explore drivers and barriers to using quantitative analysis through an online survey.
The impact of regional Tc-HMPAO single-photon-emission computed tomography (SPECT) imaging on clinician diagnostic confidence in a mixed cognitive impairment sample
Prosser AMJ, Tossici-Bolt L and Kipps CM
To assess the clinical impact of regional cerebral blood flow (rCBF) single-photon-emission computed tomography (SPECT) imaging on diagnosis and clinician diagnostic confidence in a cohort of individuals with cognitive impairment.
Occipital lobe and posterior cingulate perfusion in the prediction of dementia with Lewy body pathology in a clinical sample
Prosser AMJ, Tossici-Bolt L and Kipps CM
The aim of this study was to investigate the diagnostic value of occipital lobe and posterior cingulate perfusion in predicting dopamine transporter imaging outcome using a quantitative measure of analysis.
Imaging Care Requirements: Use of Functional Neuroimaging to Predict Dementia Caregiver Burden
Prosser AMJ, Spreadbury JH, Tossici-Bolt L and Kipps CM
Dementia caregivers frequently report high stress, with increased burden associated with worse outcomes for both patients and caregivers. Although many studies relate clinical phenotypes to burden, the relationship between imaging pathology and burden, irrespective of diagnosis, is unknown. This study investigated the relationship between caregiver burden and patient regional cerebral blood flow in dementia.

research projects:

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